CD3D Antikörper (AA 127-171)

Produktnummer ABIN7193637

Produktdetails anti-CD3D Antikörper

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Bindungsspezifität: AA 127-171

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3D Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: CD3D Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD3D (AA: 127-171) expressed in E. Coli.

Klon: 6B6B12

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200-1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CD3D

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Andere Bezeichnung: CD3D (CD3D Produkte)

Synonyme: CD3-DELTA antikoerper, T3D antikoerper, CD3 antikoerper, T3d antikoerper, CD3d molecule antikoerper, CD3 antigen, delta polypeptide antikoerper, CD3D antikoerper, Cd3d antikoerper

Hintergrund:

Description:

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]

Aliases: T3D, IMD19, CD3-DELTA

Molekulargewicht: 18.9kDa

Gen-ID: 915

UniProt: P04234

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events