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GZMB Antikörper (AA 21-247)

GZMB Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 2G12G7 unconjugated
Produktnummer ABIN7193680
  • Target Alle GZMB Antikörper anzeigen
    GZMB (Granzyme B (GZMB))
    Bindungsspezifität
    • 18
    • 16
    • 13
    • 10
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-247
    Reaktivität
    • 132
    • 52
    • 25
    • 12
    • 4
    • 4
    • 3
    • 1
    Human
    Wirt
    • 83
    • 51
    • 3
    Maus
    Klonalität
    • 81
    • 56
    Monoklonal
    Konjugat
    • 79
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GZMB Antikörper ist unkonjugiert
    Applikation
    • 71
    • 43
    • 41
    • 37
    • 18
    • 18
    • 17
    • 14
    • 13
    • 10
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Verwendungszweck
    GZMB Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli.
    Klon
    2G12G7
    Isotyp
    IgG2a
    Top Product
    Discover our top product GZMB Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    GZMB (Granzyme B (GZMB))
    Andere Bezeichnung
    GZMB (GZMB Produkte)
    Synonyme
    CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
    Hintergrund

    Description:

    This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

    Aliases: C11, HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1

    Molekulargewicht
    28kDa
    Gen-ID
    3002
    UniProt
    P10144
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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