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Cyclin D1 Antikörper (AA 1-295)

Name: Cyclin D1 Antikörper (AA 1-295)
Brand: antibodies-online
SKU: ABIN7193695
Price: 614.71 EUR
Availability: InStock

CCND1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 1F7F5 unconjugated

Western blot analysis using CCND1 mAb against human CCND1 (AA: 1-295) recombinant protein. (Cyclin D1 Antikörper (AA 1-295))

Immunohistochemical analysis of paraffin-embedded brain tissues using CCND1 mouse mAb with DAB staining. (Cyclin D1 Antikörper (AA 1-295))

IHC

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (Cyclin D1 Antikörper (AA 1-295))

ELISA

Western blot analysis using CCND1 mAb against HEK293-6e (1) and CCND1 (AA: 1-295)-hIgGFc transfected HEK293 (2) cell lysate. (Cyclin D1 Antikörper (AA 1-295))

Western blot analysis using CCND1 mouse mAb against LNCAP (1), A431 (2), and NIH/3T3 (3) cell lysate. (Cyclin D1 Antikörper (AA 1-295))

Flow cytometric analysis of Hela cells using CCND1 mouse mAb (green) and negative control (red). (Cyclin D1 Antikörper (AA 1-295))

FACS

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using CCND1 mouse mAb with DAB staining. (Cyclin D1 Antikörper (AA 1-295))

IHC

7 Abbildungen

Produktnummer ABIN7193695

Datenblatt (PDF)

Target Alle Cyclin D1 (CCND1) Antikörper anzeigen

Cyclin D1 (CCND1)
Bindungsspezifität
22

20

16

16

12

11

9

9

8

7

7

7

6

6

5

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-295
Reaktivität
235

126

121

40

20

18

16

12

10

9

3

3

3

3

3

2

2

1

1

1

1

1

1
Human
Wirt
203

54

1
Maus
Passende Sekundärantikörper
Klonalität
193

63
Monoklonal
Konjugat
118

25

20

9

7

5

5

5

5

5

5

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser Cyclin D1 Antikörper ist unkonjugiert
Applikation
195

86

64

61

41

30

28

27

23

20

19

12

6

5

3

2

2

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck

CCND1 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human CCND1 (AA: 1-295) expressed in E. Coli.

Klon

1F7F5

Isotyp

IgG1

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CCND1 Reaktivität: Human, Ratte, Maus, Affe WB, IHC, FACS, IF, StM Wirt: Maus Monoclonal DCS-6 unconjugated

anti-Cyclin D1 (CCND1) (AA 1-295) antibody
CCND1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200-1/400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target

Cyclin D1 (CCND1)

Andere Bezeichnung

CCND1 (CCND1 Produkte)

Synonyme

BCL1 antikoerper, D11S287E antikoerper, PRAD1 antikoerper, U21B31 antikoerper, AI327039 antikoerper, CycD1 antikoerper, Cyl-1 antikoerper, bcl-1 antikoerper, cD1 antikoerper, cb161 antikoerper, cycd1 antikoerper, etID37810.7 antikoerper, fb52e01 antikoerper, fc45c08 antikoerper, fc83a12 antikoerper, id:ibd1198 antikoerper, wu:fb52e01 antikoerper, wu:fc45c08 antikoerper, wu:fc83a12 antikoerper, ccnd1b antikoerper, prad1 antikoerper, ccnd1 antikoerper, ccnd1a antikoerper, bcl1 antikoerper, d11s287e antikoerper, u21b31 antikoerper, CCND1 antikoerper, cyclin D1 antikoerper, cyclin D1 S homeolog antikoerper, cyclin D1 L homeolog antikoerper, CCND1 antikoerper, Ccnd1 antikoerper, ccnd1 antikoerper, ccnd1.S antikoerper, ccnd1.L antikoerper

Hintergrund

Description:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers.
Aliases: BCL1, PRAD1, U21B31, D11S287E

Molekulargewicht

33.7kDa

Gen-ID

595

UniProt

P24385

Pathways

PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling