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MSH6 Antikörper (AA 374-540)

Name: MSH6 Antikörper (AA 374-540)
Brand: antibodies-online
SKU: ABIN7193706
Price: 614.71 EUR
Availability: InStock

MSH6 Reaktivität: Human WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 7D9H5 unconjugated

Western blot analysis using MSH6 mAb against human MSH6 (AA: 374-540) recombinant protein. (MSH6 Antikörper (AA 374-540))

Immunofluorescence analysis of Hela cells using MSH6 mouse mAb (green). (MSH6 Antikörper (AA 374-540))

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (MSH6 Antikörper (AA 374-540))

ELISA

Western blot analysis using MSH6 mAb against HEK293-6e (1) and MSH6 (AA: 374-540)-hIgGFc transfected HEK293-6e (2) cell lysate. (MSH6 Antikörper (AA 374-540))

Western blot analysis using MSH6 mouse mAb against SH-SY5Y (1), Hela (2), PC-3 (3), HCT116 (4), HEK293 (5), A549 (6), and HepG2 (7) cell lysate. (MSH6 Antikörper (AA 374-540))

Flow cytometric analysis of Hela cells using MSH6 mouse mAb (green) and negative control (red). (MSH6 Antikörper (AA 374-540))

FACS

Immunohistochemical analysis of paraffin-embedded colon tissues using MSH6 mouse mAb with DAB staining. (MSH6 Antikörper (AA 374-540))

IHC

Immunohistochemical analysis of paraffin-embedded brain tumor tissues using MSH6 mouse mAb with DAB staining. (MSH6 Antikörper (AA 374-540))

IHC

8 Abbildungen

Produktnummer ABIN7193706

Datenblatt (PDF)

Target Alle MSH6 Antikörper anzeigen

MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
Bindungsspezifität
15

7

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 374-540
Reaktivität
75

35

27

7

4

2

1

1

1
Human
Wirt
56

16

3
Maus
Passende Sekundärantikörper
Klonalität
44

31
Monoklonal
Konjugat
43

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser MSH6 Antikörper ist unkonjugiert
Applikation
51

24

23

18

14

13

11

8

7

6

5

5

4

3

3

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck

MSH6 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human MSH6 (AA: 374-540) expressed in E. Coli.

Klon

7D9H5

Isotyp

IgG2b

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anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1-100) antibody
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Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target

MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Andere Bezeichnung

MSH6 (MSH6 Produkte)

Synonyme

GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper

Hintergrund

Description:
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Aliases: GTBP, HSAP, p160, GTMBP, HNPCC5

Molekulargewicht

152.8kDa

Gen-ID

2956

UniProt

P52701

Pathways

DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response