MICB Antikörper (AA 23-309)

Produktnummer ABIN7193766

Produktdetails anti-MICB Antikörper

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Bindungsspezifität: AA 23-309

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MICB Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Verwendungszweck: MICB Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MICB (AA: 23-309) expressed in HEK293-6e cells supernatant.

Klon: 1B2F11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Andere Bezeichnung: MICB (MICB Produkte)

Synonyme: PERB11.2 antikoerper, MHC class I polypeptide-related sequence B antikoerper, MHC class I-related protein-like antikoerper, MICB antikoerper, LOC512825 antikoerper

Hintergrund:

Description:

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Aliases: PERB11.2

Molekulargewicht: 42.6kDa

Gen-ID: 4277

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response