Prominin 2 Antikörper (AA 301-400) (Cy7)
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- Target Alle Prominin 2 (PROM2) Antikörper anzeigen
- Prominin 2 (PROM2)
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Prominin 2 Antikörper ist konjugiert mit Cy7
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Prominin 2
- Isotyp
- IgG
- Top Product
- Discover our top product PROM2 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Prominin 2 (PROM2)
- Andere Bezeichnung
- Prominin 2 (PROM2 Produkte)
- Synonyme
- PROML2 antikoerper, Prom-rp antikoerper, Promrp antikoerper, Trprp antikoerper, AI507243 antikoerper, PROM2 antikoerper, prom3 antikoerper, proml3 antikoerper, fd36c02 antikoerper, fo25d03 antikoerper, wu:fd36c02 antikoerper, prom-2 antikoerper, prominin 2 antikoerper, prominin 2 L homeolog antikoerper, PROM2 antikoerper, Prom2 antikoerper, prom2 antikoerper, prom2.L antikoerper
- Hintergrund
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Synonyms: PROML2, Prominin-2, PROM-2, Prominin-like protein 2, hPROML2, PROM2, UNQ2521/PRO6014
Background: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30 % , but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
- Gen-ID
- 150696
- UniProt
- Q8N271
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