PDLIM7 Antikörper (AA 86-280)
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- Target Alle PDLIM7 Antikörper anzeigen
- PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))
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Bindungsspezifität
- AA 86-280
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PDLIM7 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- PDLIM7 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PDLIM7 (AA: 86-280) expressed in HEK293-6e cells supernatant.
- Klon
- 3B3B3
- Isotyp
- IgG1
- Top Product
- Discover our top product PDLIM7 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))
- Andere Bezeichnung
- PDLIM7 (PDLIM7 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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Description:
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Aliases: LMP1, LMP3
- Molekulargewicht
- 49.8kDa
- Gen-ID
- 9260
- UniProt
- Q9NR12
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