SIRPB1 Antikörper (AA 72-309)

Produktnummer ABIN7193917

Produktdetails anti-SIRPB1 Antikörper

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Bindungsspezifität: AA 72-309

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIRPB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: CD172b Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD172b (AA: 72-309) expressed in E. Coli.

Klon: 1B1G4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Andere Bezeichnung: CD172b (SIRPB1 Produkte)

Hintergrund:

Description:

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: SIRPB1, SIRP-BETA-1

Molekulargewicht: 43.2kDa

Gen-ID: 10326

UniProt: O00241