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RORB Antikörper (AA 385-470) (Biotin)

RORB Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN715873
  • Target Alle RORB Antikörper anzeigen
    RORB (RAR-Related Orphan Receptor B (RORB))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 385-470
    Reaktivität
    • 47
    • 26
    • 25
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Maus, Ratte
    Wirt
    • 53
    • 8
    Kaninchen
    Klonalität
    • 53
    • 8
    Polyklonal
    Konjugat
    • 28
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RORB Antikörper ist konjugiert mit Biotin
    Applikation
    • 47
    • 22
    • 19
    • 13
    • 13
    • 8
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RORB
    Isotyp
    IgG
    Top Product
    Discover our top product RORB Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    RORB (RAR-Related Orphan Receptor B (RORB))
    Andere Bezeichnung
    ROR beta (RORB Produkte)
    Synonyme
    RORB antikoerper, Nr1f2 antikoerper, LOC100226267 antikoerper, NR1F2 antikoerper, ROR-BETA antikoerper, RZR-BETA antikoerper, RZRB antikoerper, bA133M9.1 antikoerper, nr1f2 antikoerper, rzrb antikoerper, sb:eu943 antikoerper, RZR-beta antikoerper, Rorbeta antikoerper, RAR related orphan receptor B antikoerper, RAR-related orphan receptor B antikoerper, RAR-related orphan receptor beta antikoerper, RORB antikoerper, Rorb antikoerper, rorb antikoerper
    Hintergrund

    Synonyms: NR1F2, Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, ROR BETA, Rorb, RORB_HUMAN, RZR BETA, RZRB.

    Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)

    Gen-ID
    6096
    UniProt
    Q92753
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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