EIF2A Antikörper (pSer51)

Produktnummer ABIN7203754

Produktdetails anti-EIF2A Antikörper

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Bindungsspezifität: pSer51

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: eIF2α (phospho Ser51) Polyclonal Antibody

Spezifität: Phospho-eIF2α (S51) Polyclonal Antibody detects endogenous levels of eIF2α protein only when phosphorylated at S51.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human eIF2alpha Phospho-Ser51

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:50-1:200), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu EIF2A

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Andere Bezeichnung: eIF2alpha (EIF2A Produkte)

Synonyme: ATEIF2-A2 antikoerper, EIF2-A2 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, EIF-2A antikoerper, MST089 antikoerper, MSTP004 antikoerper, MSTP089 antikoerper, D030048D22 antikoerper, D3Ertd194e antikoerper, im:7145971 antikoerper, zgc:110460 antikoerper, DDBDRAFT_0185936 antikoerper, DDBDRAFT_0234177 antikoerper, DDB_0185936 antikoerper, DDB_0234177 antikoerper, Eif2a antikoerper, eif2a antikoerper, eif2alpha antikoerper, EIF2A antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eIF2alpha antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, eukaryotic translation initiation factor 2A antikoerper, eukaryotic translation initiation factor 2A, 65kDa antikoerper, eukaryotic translation initiation factor 2A S homeolog antikoerper, eukaryotic translation initiation factor antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2 ALPHA antikoerper, EIF2A antikoerper, Eif2a antikoerper, eif2a antikoerper, eIF2a antikoerper, eif2a.S antikoerper, eif2A antikoerper, eIF-2alpha antikoerper

Hintergrund: Rabbit Anti-eIF2α (phospho Ser51) Polyclonal Antibody,EIF2S1, EIF2A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha,The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).,Eukaryotic translation initiation factor 2 subunit 1

Gen-ID: 1965

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly