GDF2 Antikörper (AA 371-420)

Produktnummer ABIN7227494

Produktdetails anti-GDF2 Antikörper

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Bindungsspezifität: AA 371-420

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: BMP-9 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of BMP-9

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human BMP-9 protein at AA range: 371-420

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Andere Bezeichnung: BMP-9 (GDF2 Produkte)

Synonyme: bmp9 antikoerper, BMP-9 antikoerper, BMP9 antikoerper, Bmp9 antikoerper, DSL1 antikoerper, growth differentiation factor 2 antikoerper, gdf2 antikoerper, GDF2 antikoerper, Gdf2 antikoerper

Hintergrund: Rabbit Anti-BMP-9 Polyclonal Antibody,Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9,GDF2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in GDF2 are associated with hereditary hemorrhagic telangiectasia.,BMP-9

Gen-ID: 2658

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis