CAMKK2 Antikörper (AA 501-588)

Produktnummer ABIN716426

Produktdetails anti-CAMKK2 Antikörper

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Bindungsspezifität: AA 501-588

Reaktivität: Human, Maus, Ratte, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMKK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Schwein, Ratte, Schaf

Homologie: Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAMKK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CAMKK2 Antikörper (ABIN716426)

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Zhao, Zhang, Liu, Zhang, Hao, Li, Chen, Shen, Tang, Min, Meng, Wang, Yi, Zhang: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." in: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).

Wang, Zhao, Yu, Feng, Zhang, Kou, Chu, Cui, Li, Zhang, Shen, Min: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." in: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).

Details zu CAMKK2

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Andere Bezeichnung: Camkk2 (CAMKK2 Produkte)

Synonyme: CAMKK antikoerper, CAMKKB antikoerper, 6330570N16Rik antikoerper, AW061083 antikoerper, mKIAA0787 antikoerper, camk2b antikoerper, fj90d04 antikoerper, wu:fj90d04 antikoerper, si:dkey-174n20.2 antikoerper, CAMKK2 antikoerper, calcium/calmodulin dependent protein kinase kinase 2 antikoerper, calcium/calmodulin-dependent protein kinase kinase 2, beta antikoerper, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antikoerper, calcium/calmodulin dependent protein kinase II beta antikoerper, calcium/calmodulin-dependent protein kinase kinase 2 antikoerper, CAMKK2 antikoerper, Camkk2 antikoerper, camk2b1 antikoerper, CAMK2B antikoerper, camkk2 antikoerper

Hintergrund:

Synonyms: Calcium/calmodulin dependent protein kinase beta, Calcium/calmodulin dependent protein kinase kinase 2, Calcium/calmodulin dependent protein kinase kinase beta, CaM kinase kinase beta, CaM KK beta, CAMKK 2, CAMKK, CaMKK beta, CAMKK beta protein, CAMKKB.

Background: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq, Jul 2008].

Gen-ID: 10645

Pathways: AMPK Signaling