Osteopontin Antikörper (AA 230-310)

Produktnummer ABIN7216326

Produktdetails anti-Osteopontin Antikörper

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Bindungsspezifität: AA 230-310

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Osteopontin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: OPN Polyclonal Antibody

Spezifität: OPN Polyclonal Antibody detects endogenous levels of OPN protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human OPN at AA range: 230-310

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Osteopontin

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Andere Bezeichnung: OPN (SPP1 Produkte)

Synonyme: BNSP antikoerper, BSPI antikoerper, ETA-1 antikoerper, OPN antikoerper, 2AR antikoerper, Apl-1 antikoerper, Bsp antikoerper, Eta antikoerper, OP antikoerper, Opn antikoerper, Opnl antikoerper, Ric antikoerper, Spp-1 antikoerper, OSP antikoerper, zgc:111821 antikoerper, secreted phosphoprotein 1 antikoerper, SPP1 antikoerper, Spp1 antikoerper, spp1 antikoerper

Hintergrund: Rabbit Anti-OPN Polyclonal Antibody,SPP1, BNSP, OPN, PSEC0156, Osteopontin, Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, SPP-1, Urinary stone protein, Uropontin,Secreted phosphoprotein 1 encoded by SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix. Secreted phosphoprotein 1 is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to secreted phosphoprotein 1. Secreted phosphoprotein 1 is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for SPP1.,Osteopontin

Molekulargewicht: observerd band 60kDa

Gen-ID: 6696

UniProt: P10451

Pathways: Regulation of Cell Size