TGFB1 Antikörper (AA 310-390)

Produktnummer ABIN7217302

Produktdetails anti-TGFB1 Antikörper

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Bindungsspezifität: AA 310-390

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: TGFβ1 Polyclonal Antibody

Spezifität: TGFβ1 Polyclonal Antibody detects endogenous levels of TGFβ1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human TGFbeta1 at AA range: 310-390

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TGFB1

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Andere Bezeichnung: TGFbeta1 (TGFB1 Produkte)

Synonyme: CED antikoerper, DPD1 antikoerper, LAP antikoerper, TGFB antikoerper, TGFbeta antikoerper, TGF-beta antikoerper, TGF-BETA-1 antikoerper, TGF-beta5 antikoerper, ced antikoerper, dpd1 antikoerper, lap antikoerper, tgf-beta antikoerper, tgfb antikoerper, tgfb5 antikoerper, tgfbeta antikoerper, TGF-beta1 antikoerper, TGFbeta1 antikoerper, Tgfb antikoerper, Tgfb-1 antikoerper, ai39657 antikoerper, tgfb1 antikoerper, wu:fb13a07 antikoerper, xx:ai39657 antikoerper, TGFB1 antikoerper, csd antikoerper, cdb1 antikoerper, cdg2 antikoerper, csd1 antikoerper, csd2 antikoerper, csd3 antikoerper, ebmd antikoerper, lcd1 antikoerper, bigh3 antikoerper, cdgg1 antikoerper, betaig-h3 antikoerper, TGFB4 antikoerper, transforming growth factor beta 1 antikoerper, transforming growth factor beta-1 antikoerper, transforming growth factor beta 1 L homeolog antikoerper, transforming growth factor, beta 1 antikoerper, transforming growth factor, beta 1a antikoerper, transforming growth factor beta induced L homeolog antikoerper, TGFB1 antikoerper, Tgfb1 antikoerper, tgfb1.L antikoerper, tgfb1a antikoerper, tgfbi.L antikoerper

Hintergrund: Rabbit Anti-TGFβ1 Polyclonal Antibody,TGFB1, TGFB, Transforming growth factor beta-1, TGF-beta-1,TGFB1 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. The Transforming growth factor beta-1 regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.,Transforming growth factor beta-1

Molekulargewicht: observerd band 44kDa

Gen-ID: 7040

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie, Cancer Immune Checkpoints