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ABI2 Antikörper (AA 100-200)

ABI2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7265360
  • Target Alle ABI2 Antikörper anzeigen
    ABI2 (Abl-Interactor 2 (ABI2))
    Bindungsspezifität
    • 15
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 100-200
    Reaktivität
    • 40
    • 16
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 39
    • 2
    Kaninchen
    Klonalität
    • 40
    • 1
    Polyklonal
    Konjugat
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABI2 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 21
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    ABI2 Rabbit pAb
    Sequenz
    HKEKVARREI GILTTNKNTS RTHKIIAPAN LERPVRYIRK PIDYTILDDI GHGVKWLLRF KVSTQNMKMG GLPRTTPPTQ KPPSPPMSGK GTLGRHSPYR T
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
    Isotyp
    IgG
    Top Product
    Discover our top product ABI2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ABI2 (Abl-Interactor 2 (ABI2))
    Andere Bezeichnung
    ABI2 (ABI2 Produkte)
    Synonyme
    ABI-2 antikoerper, ABI2B antikoerper, AIP-1 antikoerper, AblBP3 antikoerper, SSH3BP2 antikoerper, argBPIA antikoerper, argBPIB antikoerper, 8430425M24Rik antikoerper, AI839867 antikoerper, C130078H13 antikoerper, abl interactor 2 antikoerper, abl-interactor 2 antikoerper, ABI2 antikoerper, abi2 antikoerper, Abi2 antikoerper
    Hintergrund
    Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity. In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity. Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity. Also required for nascent adherens junction assembly in epithelial cells.,ABI2,ABI-2,ABI2B,AIP-1,AblBP3,SSH3BP2,argBP1,argBPIA,argBPIB,Cancer,Tumor suppressors,ABI2
    Molekulargewicht
    44kDa/52kDa/54kDa/55kDa
    Gen-ID
    10152
    UniProt
    Q9NYB9
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