ADRA2C Antikörper (AA 240-380)

Produktnummer ABIN7265501

Produktdetails anti-ADRA2C Antikörper

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Bindungsspezifität: AA 240-380

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: ADRA2C Rabbit pAb

Sequenz: RTRTLSEKRA PVGPDGASPT TENGLGAAAG AGENGHCAPP PADVEPDESS AAAERRRRRG ALRRGGRRRA GAEGGAGGAD GQGAGPGAAE SGALTASRSP GPGGRLSRAS SRSVEFFLSR RRRARSSVCR RKVAQAREKR F

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2C (NP_000674.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ADRA2C

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Andere Bezeichnung: ADRA2C (ADRA2C Produkte)

Synonyme: ADRA2L2 antikoerper, ADRA2RL2 antikoerper, ADRARL2 antikoerper, ALPHA2CAR antikoerper, Adra-2c antikoerper, [a]2C antikoerper, alpha2-C4 antikoerper, alpha2C antikoerper, zgc:194523 antikoerper, zgc:194541 antikoerper, adra2c antikoerper, ADRA2B antikoerper, ADRA2C antikoerper, adrenoceptor alpha 2C antikoerper, adrenergic receptor, alpha 2c antikoerper, ADRA2C antikoerper, Adra2c antikoerper, adra2c antikoerper

Hintergrund: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],ADRA2L2,ADRA2RL2,ADRARL2,ALPHA2CAR,ADRA2C,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,ADRA2C

Gen-ID: 152

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process