AKT 1/2/3 Antikörper (pSer472)
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- Target Alle AKT 1/2/3 Produkte
- AKT 1/2/3
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Bindungsspezifität
- pSer472
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AKT 1/2/3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Verwendungszweck
- Phospho-AKT1-S473+AKT2-S474+AKT3-S472 Rabbit pAb
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Phosphorylated Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A phospho synthetic peptide corresponding to residues surrounding S473/S474/S472 of human AKT1/AKT2/AKT3.
- Isotyp
- IgG
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anti-AKT 1/2/3 (AA 401-479) antibody
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein WB, IF (cc), IF (p), FACS, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibodyReaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Huhn, Fisch WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), FACS, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr474) antibodyReaktivität: Human, Maus WB, IF (cc), IF (p), FACS, ELISA, IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pThr305), (pThr308), (pThr309) antibodyReaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), FACS, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (AA 278-312) antibodyReaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB43841 unconjugated
anti-AKT 1/2/3 (AA 431-480) antibodyReaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibodyReaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- AKT 1/2/3
- Andere Bezeichnung
- AKT1/AKT2/AKT3 (AKT 1/2/3 Produkte)
- Hintergrund
- The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011],AKT1/AKT2/AKT3,Protein phosphorylation,AKT1/AKT2/AKT3
- Molekulargewicht
- 48kDa/55kDa/51kDa/54kDa
- Gen-ID
- 207, 208, 10000
- UniProt
- P31749, P31751, Q9Y243
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