ANKRD15 Antikörper (AA 900-1000)

Produktnummer ABIN7265613

Produktdetails anti-ANKRD15 Antikörper

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Bindungsspezifität: AA 900-1000

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: KANK1 Rabbit pAb

Sequenz: GNYLGYTCKC GGLQSGSPLS SQTSQPEQEV GTSEGKPISS LDAFPTQEGT LSPVNLTDDQ IAAGLYACTN NESTLKSIMK KKDGNKDSNG AKKNLQFVGI N

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human KANK1 (NP_055973.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ANKRD15

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Andere Bezeichnung: KANK1 (ANKRD15 Produkte)

Synonyme: ANKRD15 antikoerper, CPSQ2 antikoerper, KANK antikoerper, A930031B09Rik antikoerper, AU015049 antikoerper, AW121052 antikoerper, Ankrd15 antikoerper, D330024H06Rik antikoerper, mKIAA0172 antikoerper, KANK1 antikoerper, ankrd15 antikoerper, kank1.2 antikoerper, DMRT1 antikoerper, KN motif and ankyrin repeat domains 1 antikoerper, KN motif and ankyrin repeat domains 1 L homeolog antikoerper, doublesex and mab-3 related transcription factor 1 antikoerper, KANK1 antikoerper, Kank1 antikoerper, kank1.L antikoerper, DMRT1 antikoerper

Hintergrund: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5,9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.,KANK1,ANKRD15,CPSQ2,KANK,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,KANK1

Molekulargewicht: 129kDa/147kDa

Gen-ID: 23189

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization