ACLY Antikörper (AA 752-1101)

Produktnummer ABIN7265716

Produktdetails anti-ACLY Antikörper

Target: ACLY (ATP Citrate Lyase (ACLY))

Bindungsspezifität: AA 752-1101

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACLY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: ACLY Rabbit pAb

Sequenz: FSSEVQFGHA GACANQASET AVAKNQALKE AGVFVPRSFD ELGEIIQSVY EDLVANGVIV PAQEVPPPTV PMDYSWAREL GLIRKPASFM TSICDERGQE LIYAGMPITE VFKEEMGIGG VLGLLWFQKR LPKYSCQFIE MCLMVTADHG PAVSGAHNTI ICARAGKDLV SSLTSGLLTI GDRFGGALDA AAKMFSKAFD SGIIPMEFVN KMKKEGKLIM GIGHRVKSIN NPDMRVQILK DYVRQHFPAT PLLDYALEVE KITTSKKPNL ILNVDGLIGV AFVDMLRNCG SFTREEADEY IDIGALNGIF VLGRSMGFIG HYLDQKRLKQ GLYRHPWDDI SYVLPEHMSM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 752-1101 of human ACLY (NP_001087.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ACLY

Target: ACLY (ATP Citrate Lyase (ACLY))

Andere Bezeichnung: ACLY (ACLY Produkte)

Synonyme: ACLY antikoerper, DDBDRAFT_0205389 antikoerper, DDBDRAFT_0235360 antikoerper, DDB_0205389 antikoerper, DDB_0235360 antikoerper, ACL antikoerper, BcDNA:LD21334 antikoerper, CG8322 antikoerper, DmATPCL antikoerper, Dmel\\CG8322 antikoerper, anon-WO0140519.179 antikoerper, dATPCL antikoerper, l(2)01466 antikoerper, l(2)k09217 antikoerper, n(2)k09217 antikoerper, ATPCL antikoerper, CLATP antikoerper, A730098H14Rik antikoerper, AW538652 antikoerper, Clatp antikoerper, acly antikoerper, cb722 antikoerper, zgc:92008 antikoerper, ATP citrate lyase antikoerper, ATP citrate lyase S homeolog antikoerper, ATP-citrate synthase antikoerper, citrate synthase, mitochondrial antikoerper, atp-citrate synthase antikoerper, ATP citrate lyase a antikoerper, ACLY antikoerper, acly.S antikoerper, LOC587157 antikoerper, acly antikoerper, ATPCL antikoerper, LOC5564509 antikoerper, CpipJ_CPIJ010291 antikoerper, Bm1_26245 antikoerper, ACL antikoerper, Acly antikoerper, aclya antikoerper

Hintergrund: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,ACLY,ACL,ATPCL,CLATP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,ACLY

Molekulargewicht: 91kDa/119kDa/120kDa

Gen-ID: 47

UniProt: P53396

Pathways: Warburg Effekt