cb1023 antikoerper, baiap2l1 antikoerper, zgc:85624 antikoerper, RGD1308452 antikoerper, BAIAP2L1 antikoerper, MGC131079 antikoerper, 1300006M19Rik antikoerper, AI585895 antikoerper, IRTKS antikoerper, zgc:110192 antikoerper, BAI1-associated protein 2-like 1a antikoerper, BAI1-associated protein 2-like 1 antikoerper, BAI1 associated protein 2 like 1 antikoerper, BAI1 associated protein 2 like 1 L homeolog antikoerper, BAI1-associated protein 2-like 1b antikoerper, baiap2l1a antikoerper, Baiap2l1 antikoerper, BAIAP2L1 antikoerper, baiap2l1.L antikoerper, baiap2l1b antikoerper
Hintergrund
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.,BAIAP2L1,IRTKS,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,BAIAP2L1