MGC98869 antikoerper, BRMS1 antikoerper, BRMS1L antikoerper, AV003220 antikoerper, AW554636 antikoerper, si:zc188c22.3 antikoerper, si:zc194c5.2 antikoerper, wu:fb57b08 antikoerper, zgc:56414 antikoerper, breast cancer metastasis suppressor 1 antikoerper, breast cancer metastasis-suppressor 1 antikoerper, breast cancer metastasis suppressor 1 L homeolog antikoerper, BRMS1 antikoerper, Brms1 antikoerper, brms1.L antikoerper, brms1 antikoerper
Hintergrund
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.,BRMS1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,BRMS1