This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012],AFCP, HEL-S-66, MCP,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytoskeleton,Cytoskeleton_Microfilaments,Immunology & Inflammation,Signal Transduction,CAPG