CARD16 Antikörper (AA 50-150)

Produktnummer ABIN7266127

Produktdetails anti-CARD16 Antikörper

Target: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Bindungsspezifität: AA 50-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: CARD16 Rabbit pAb

Sequenz: VMDKTRALID SVIPKGAQAC QICITYICEE DSYLAETLGL SAALQAVQDN PAMPTCSSPE GRIKLCFLED AQRIWKQKLQ RCHVQNTIIK WSERYTSGSF E

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CARD16 (NP_001017534.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CARD16

Target: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Andere Bezeichnung: CARD16 (CARD16 Produkte)

Synonyme: COP antikoerper, COP1 antikoerper, PSEUDO-ICE antikoerper, caspase recruitment domain family member 16 antikoerper, CARD16 antikoerper

Hintergrund: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.,CARD16,COP,COP1,PSEUDO-ICE,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD16

Molekulargewicht: 10kDa/22kDa

Gen-ID: 114769

UniProt: Q5EG05