CEP290 Antikörper (AA 950-1050)

Produktnummer ABIN7266277

Produktdetails anti-CEP290 Antikörper

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Bindungsspezifität: AA 950-1050

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP290 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: CEP290 Rabbit pAb

Sequenz: QKVVDNSVSL SELELANKQY NELTAKYRDI LQKDNMLVQR TSNLEHLECE NISLKEQVES INKELEITKE KLHTIEQAWE QETKLGNESS MDKAKKSITN S

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 950-1050 of human CEP290 (NP_079390.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Andere Bezeichnung: CEP290 (CEP290 Produkte)

Hintergrund: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.,CEP290,3H11Ag,BBS14,CT87,JBTS5,LCA10,MKS4,NPHP6,POC3,SLSN6,rd16,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Neuroscience,CEP290

Molekulargewicht: 180kDa/290kDa

Gen-ID: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase