CMKLR1 Antikörper (AA 250-350)
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- Target Alle CMKLR1 Antikörper anzeigen
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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Bindungsspezifität
- AA 250-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CMKLR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Verwendungszweck
- CMKLR1 Rabbit pAb
- Sequenz
- NRLAKTKKPF KIIVTIIITF FLCWCPYHTL NLLELHHTAM PGSVFSLGLP LATALAIANS CMNPILYVFM GQDFKKFKVA LFSRLVNALS EDTGHSSYPS H
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CMKLR1 (NP_001135815.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CMKLR1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Andere Bezeichnung
- CMKLR1 (CMKLR1 Produkte)
- Synonyme
- CHEMERINR antikoerper, ChemR23 antikoerper, DEZ antikoerper, RVER1 antikoerper, Gpcr27 antikoerper, mcmklr1 antikoerper, si:ch211-240b21.3 antikoerper, CMLKR1 antikoerper, Cmklr-1 antikoerper, GPCR antikoerper, chemerin chemokine-like receptor 1 antikoerper, chemokine-like receptor 1 antikoerper, CMKLR1 antikoerper, Cmklr1 antikoerper, cmklr1 antikoerper
- Hintergrund
- Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i/G(o and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2, TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis PubMed:27716822. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2 and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism.,CMKLR1,CHEMERINR,ChemR23,DEZ,RVER1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,CMKLR1
- Molekulargewicht
- 42kDa
- Gen-ID
- 1240
- UniProt
- Q99788
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