C6orf150 Antikörper (pSer420)

Produktnummer ABIN7266387

Produktdetails anti-C6orf150 Antikörper

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Bindungsspezifität: pSer420

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C6orf150 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Phospho-CGAS-S420 Rabbit pAb

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu C6orf150

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Andere Bezeichnung: CGAS (C6orf150 Produkte)

Synonyme: C6orf150 antikoerper, cGAS antikoerper, h-cGAS antikoerper, Mab-21 domain containing 1 antikoerper, cyclic GMP-AMP synthase antikoerper, MB21D1 antikoerper, CGAS antikoerper

Hintergrund: The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],E330016A19Rik, cGAS,CGAS

Gen-ID: 214763

UniProt: Q8C6L5

Pathways: Activation of Innate immune Response