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CRTC1 Antikörper (AA 1-200)

CRTC1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7266518
  • Target Alle CRTC1 Antikörper anzeigen
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Bindungsspezifität
    • 22
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-200
    Reaktivität
    • 67
    • 37
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 13
    • 1
    Kaninchen
    Klonalität
    • 55
    • 14
    Polyklonal
    Konjugat
    • 32
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRTC1 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 25
    • 20
    • 13
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    CRTC1 Rabbit pAb
    Sequenz
    MATSNNPRKF SEKIALHNQK QAEETAAFEE VMKDLSLTRA ARLQLQKSQY LQLGPSRGQY YGGSLPNVNQ IGSGTMDLPF QTPFQSSGLD TSRTTRHHGL VDRVYRERGR LGSPHRRPLS VDKHGRQADS CPYGTMYLSP PADTSWRRTN SDSALHQSTM TPTQPESFSS GSQDVHQKRV LLLTVPGMEE TTSEADKNLS
    Kreuzreaktivität
    Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRTC1 (NP_056136.2).
    Isotyp
    IgG
    Top Product
    Discover our top product CRTC1 Primärantikörper
  • Applikationshinweise
    WB,1:200 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Andere Bezeichnung
    CRTC1 (CRTC1 Produkte)
    Synonyme
    MECT1 antikoerper, TORC-1 antikoerper, TORC1 antikoerper, WAMTP1 antikoerper, AI413414 antikoerper, Mect1 antikoerper, R74955 antikoerper, mKIAA0616 antikoerper, CRTC1 antikoerper, crtc1 antikoerper, fc68c05 antikoerper, pde4cb antikoerper, si:ch211-255d18.1 antikoerper, si:ch211-255d18.8 antikoerper, wu:fc68c05 antikoerper, CREB regulated transcription coactivator 1 antikoerper, CREB regulated transcription coactivator 1b antikoerper, CRTC1 antikoerper, Crtc1 antikoerper, crtc1 antikoerper, crtc1b antikoerper
    Hintergrund
    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.,CRTC1,MECT1,TORC-1,TORC1,WAMTP1,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,CRTC1
    Molekulargewicht
    62kDa/67kDa/68kDa
    Gen-ID
    23373
    UniProt
    Q6UUV9
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