Deoxyuridine Triphosphatase (DUT) (AA 89-252) Antikörper
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- Target Alle Deoxyuridine Triphosphatase (DUT) Antikörper anzeigen
- Deoxyuridine Triphosphatase (DUT)
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Bindungsspezifität
- AA 89-252
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Verwendungszweck
- DUT Rabbit pAb
- Sequenz
- PAPGPETPAI SPSKRARPAE VGGMQLRFAR LSEHATAPTR GSARAAGYDL YSAYDYTIPP MEKAVVKTDI QIALPSGCYG RVAPRSGLAA KHFIDVGAGV IDEDYRGNVG VVLFNFGKEK FEVKKGDRIA QLICERIFYP EIEEVQALDD TERGSGGFGS TGKN
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 89-252 of human DUT (NP_001020419.1).
- Isotyp
- IgG
- Top Product
- Discover our top product DUT Primärantikörper
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anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibody
DUT Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 1C9 unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibodyVerified DUT Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT Reaktivität: Human, Ratte, Maus, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibodyDUT Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT Reaktivität: Human, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibodyDUT Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT Reaktivität: Human, Ratte, Maus, Hund, Fledermaus, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibodyDUT Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibodyDUT Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:100 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Deoxyuridine Triphosphatase (DUT)
- Andere Bezeichnung
- DUT (DUT Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
- This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.,DUT,dUTPase,Epigenetics & Nuclear Signaling,RNA Binding,DUT
- Molekulargewicht
- 17kDa/26kDa
- Gen-ID
- 1854
- UniProt
- P33316
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