DCLK1 Antikörper (AA 630-729)

Produktnummer ABIN7266842

Produktdetails anti-DCLK1 Antikörper

Target: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Bindungsspezifität: AA 630-729

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: DCAMKL1/DCLK1 Rabbit pAb

Sequenz: VDVDQRFSAV QVLEHPWVND DGLPENEHQL SVAGKIKKHF NTGPKPNSTA AGVSVIALDH GFTIKRSGSL DYYQQPGMYW IRPPLLIRRG RFSDEDATRM

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 630-729 of human DCAMKL1/DCAMKL1/DCLK1 (NP_004725.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DCLK1

Target: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Andere Bezeichnung: DCLK1 (DCLK1 Produkte)

Synonyme: DCLK1 antikoerper, DCAMKL1 antikoerper, dcamkl1 antikoerper, dclk1 antikoerper, wu:fc51f11 antikoerper, zgc:153709 antikoerper, MGC145348 antikoerper, CL1 antikoerper, CLICK1 antikoerper, DCDC3A antikoerper, DCLK antikoerper, 1700113D08Rik antikoerper, 2810480F11Rik antikoerper, AI836758 antikoerper, Click-I antikoerper, Cpg16 antikoerper, Dcamkl1 antikoerper, Dcl antikoerper, Dclk antikoerper, mKIAA0369 antikoerper, Ania4 antikoerper, doublecortin like kinase 1 antikoerper, doublecortin-like kinase 1a antikoerper, serine/threonine-protein kinase DCLK1 antikoerper, doublecortin-like kinase 2 antikoerper, doublecortin-like kinase 1 antikoerper, DCLK1 antikoerper, dclk1a antikoerper, LOC587664 antikoerper, dclk2 antikoerper, LOC100539645 antikoerper, Dclk1 antikoerper

Hintergrund: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.,DCLK1,CL1,CLICK1,DCAMKL1,DCDC3A,DCLK,Signal Transduction,Kinase,Neuroscience,DCLK1

Molekulargewicht: 46kDa/47kDa/81kDa/82kDa

Gen-ID: 9201

UniProt: O15075