DUSP2 Antikörper (AA 150-250)

Produktnummer ABIN7266847

Produktdetails anti-DUSP2 Antikörper

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Bindungsspezifität: AA 150-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: DUSP2 Rabbit pAb

Sequenz: ALPPTGDKTS RSDSRAPVYD QGGPVEILPY LFLGSCSHSS DLQGLQACGI TAVLNVSASC PNHFEGLFRY KSIPVEDNQM VEISAWFQEA IGFIDWVKNS G

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human DUSP2 (NP_004409.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Andere Bezeichnung: DUSP2 (DUSP2 Produkte)

Synonyme: zgc:91929 antikoerper, wu:fj40g04 antikoerper, PAC-1 antikoerper, PAC1 antikoerper, dual specificity phosphatase 2 antikoerper, dusp2 antikoerper, DUSP2 antikoerper, Dusp2 antikoerper

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.,DUSP2,PAC-1,PAC1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,DUSP2

Molekulargewicht: 34kDa

Gen-ID: 1844

UniProt: Q05923