E2F5 Antikörper (AA 197-346)
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- Target Alle E2F5 Antikörper anzeigen
- E2F5
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Bindungsspezifität
- AA 197-346
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser E2F5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- E2F5 Rabbit pAb
- Sequenz
- QLEVPIPEMG QNGQKKYQIN LKSHSGPIHV LLINKESSSS KPVVFPVPPP DDLTQPSSQS LTPVTPQKSS MATQNLPEQH VSERSQALQQ TSATDISSAG SISGDIIDEL MSSDVFPLLR LSPTPADDYN FNLDDNEGVC DLFDVQILNY
- Kreuzreaktivität
- Human
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 197-346 of human E2F5 (NP_001942.2).
- Isotyp
- IgG
- Top Product
- Discover our top product E2F5 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- E2F5
- Andere Bezeichnung
- E2F5 (E2F5 Produkte)
- Synonyme
- AU024671 antikoerper, E2F-5 antikoerper, E2f-5 antikoerper, E2F4 antikoerper, cb735 antikoerper, zgc:111879 antikoerper, E2F transcription factor 5 antikoerper, E2f5 antikoerper, e2f5 antikoerper, E2F5 antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.,E2F5,E2F-5,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,E2F5
- Molekulargewicht
- 20kDa/37kDa
- Gen-ID
- 1875
- UniProt
- Q15329
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