EIF2AK2 Antikörper (pThr446)

Produktnummer ABIN7267028

Produktdetails anti-EIF2AK2 Antikörper

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Bindungsspezifität: pThr446

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EIF2AK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Phospho-PKR/EIF2AK2-T446 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding T446 of human PKR/EIF2AK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EIF2AK2

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Andere Bezeichnung: EIF2AK2 (EIF2AK2 Produkte)

Synonyme: PKR antikoerper, pkr antikoerper, EIF2AK2 antikoerper, DKFZp469K1934 antikoerper, EIF2AK1 antikoerper, PRKR antikoerper, 2310047A08Rik antikoerper, 4732414G15Rik antikoerper, AI467567 antikoerper, AI747578 antikoerper, Pkr antikoerper, Prkr antikoerper, Tik antikoerper, eukaryotic translation initiation factor 2 alpha kinase 2 antikoerper, eukaryotic translation initiation factor 2-alpha kinase 2 antikoerper, EIF2AK2 antikoerper, eif2ak2 antikoerper, Eif2ak2 antikoerper

Hintergrund: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],EIF2AK1, PKR, PPP1R83, PRKR,Apoptosis,Autophagy,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Protein phosphorylation,Signal Transduction,Translation Control,Translational Control_Regulation of eIF2,EIF2AK2

Molekulargewicht: 62kDa

Gen-ID: 5610

UniProt: P19525

Pathways: DNA Reparatur, ER-Nucleus Signaling, Hepatitis C