PERK Antikörper (pThr982)

Produktnummer ABIN7267032

Produktdetails anti-PERK Antikörper

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Bindungsspezifität: pThr982

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PERK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Phospho-PERK-T982 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding T982 of human PERK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PERK

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Andere Bezeichnung: EIF2AK3 (EIF2AK3 Produkte)

Synonyme: EIF2AK3 antikoerper, AI427929 antikoerper, Pek antikoerper, Perk antikoerper, PEK antikoerper, PERK antikoerper, WRS antikoerper, eukaryotic translation initiation factor 2 alpha kinase 3 antikoerper, EIF2AK3 antikoerper, Eif2ak3 antikoerper

Hintergrund: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.,EIF2AK3,PEK,PERK,WRS,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF2,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Protein folding,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,Neurodegenerative Diseases,Protein phosphorylation,EIF2AK3

Molekulargewicht: 125kDa

Gen-ID: 9451

UniProt: Q9NZJ5

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response