Separase Antikörper (AA 1220-1500)
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- Target Alle Separase (ESPL1) Antikörper anzeigen
- Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))
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Bindungsspezifität
- AA 1220-1500
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Separase Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Verwendungszweck
- ESPL1 Rabbit pAb
- Sequenz
- DEILAQAYTL LALEGLNQPS NESLQKVLQS GLKFVAARIP HLEPWRASLL LIWALTKLGG LSCCTTQLFA SSWGWQPPLI KSVPGSEPSK TQGQKRSGRG RQKLASAPLR LNNTSQKGLE GRGLPCTPKP PDRIRQAGPH VPFTVFEEVC PTESKPEVPQ APRVQQRVQT RLKVNFSDDS DLEDPVSAEA WLAEEPKRRG TASRGRGRAR KGLSLKTDAV VAPGSAPGNP GLNGRSRRAK KVASRHCEER RPQRASDQAR PGPEIMRTIP EEELTDNWRK M
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1220-1500 of human ESPL1 (NP_036423.4).
- Isotyp
- IgG
- Top Product
- Discover our top product ESPL1 Primärantikörper
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anti-Extra Spindle Poles Like 1 (ESPL1) (AA 586-701) antibody
ESPL1 Reaktivität: Human ELISA, WB, IHC (p) Wirt: Maus Monoclonal 6H6 unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) antibodyESPL1 Reaktivität: Human, Maus ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (pSer1126) antibodyESPL1 Reaktivität: Human IHC (p), DB Wirt: Kaninchen Polyclonal RB7943 unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (Tyr489) antibodyESPL1 Reaktivität: Human, Maus ELISA, IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (AA 767-816) antibodyESPL1 Reaktivität: Human, Maus ELISA, IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (pSer801) antibodyESPL1 Reaktivität: Human IHC, WB, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (pSer801) antibodyESPL1 Reaktivität: Human ELISA, IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (AA 1292-1495) antibodyESPL1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) (pSer801) antibodyESPL1 Reaktivität: Human, Maus ELISA, IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Extra Spindle Poles Like 1 (ESPL1) antibodyESPL1 Reaktivität: Maus WB Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- WB,1:200 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))
- Andere Bezeichnung
- ESPL1 (ESPL1 Produkte)
- Hintergrund
- Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21, MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010],ESPL1,ESP1,SEPA,separin,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,ESPL1
- Molekulargewicht
- 197kDa/233kDa
- Gen-ID
- 9700
- UniProt
- Q14674
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