FCN3 Antikörper (AA 13-288)

Produktnummer ABIN7267202

Produktdetails anti-FCN3 Antikörper

Target: FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))

Bindungsspezifität: AA 13-288

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FCN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: FCN3 Rabbit pAb

Sequenz: LLLGGPACLK TQEHPSCPGP RELEASKVVL LPSCPGAPGS PGEKGAPGPQ GPPGPPGKMG PKGEPGPRNC RELLSQGATL SGWYHLCLPE GRALPVFCDM DTEGGGWLVF QRRQDGSVDF FRSWSSYRAG FGNQESEFWL GNENLHQLTL QGNWELRVEL EDFNGNRTFA HYATFRLLGE VDHYQLALGK FSEGTAGDSL SLHSGRPFTT YDADHDSSNS NCAVIVHGAW WYASCYRSNL NGRYAVSEAA AHKYGIDWAS GRGVGHPYRR VRMMLR

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 13-288 of human FCN3 (NP_775628.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FCN3

Target: FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))

Andere Bezeichnung: FCN3 (FCN3 Produkte)

Synonyme: FCNH antikoerper, HAKA1 antikoerper, ficolin 3 antikoerper, ficolin-3 antikoerper, FCN3 antikoerper, Fcn3 antikoerper, fcn3-A antikoerper

Hintergrund: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.,FCN3,FCNH,HAKA1,ficolin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,FCN3

Molekulargewicht: 31kDa/32kDa

Gen-ID: 8547

UniProt: O75636

Pathways: Komplementsystem