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FURIN Antikörper

FURIN Reaktivität: Human WB, IP Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7267277
  • Target Alle FURIN Antikörper anzeigen
    FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
    Reaktivität
    • 38
    • 36
    • 16
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 52
    • 3
    • 3
    Kaninchen
    Klonalität
    • 46
    • 12
    Monoklonal
    Konjugat
    • 25
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FURIN Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 17
    • 13
    • 13
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    Western Blotting (WB), Immunoprecipitation (IP)
    Verwendungszweck
    Furin Rabbit mAb
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Furin
    Isotyp
    IgG
    Top Product
    Discover our top product FURIN Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IP,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
    Andere Bezeichnung
    FURIN (FURIN Produkte)
    Synonyme
    FURIN antikoerper, furin antikoerper, si:dkey-281a24.5 antikoerper, FUR antikoerper, LOC100220259 antikoerper, PACE antikoerper, spc1 antikoerper, xfurin antikoerper, MGC82710 antikoerper, PCSK3 antikoerper, SPC1 antikoerper, 9130404I01Rik antikoerper, Fur antikoerper, Pcsk3 antikoerper, Pace antikoerper, furin, paired basic amino acid cleaving enzyme antikoerper, furin (paired basic amino acid cleaving enzyme) a antikoerper, furin (paired basic amino acid cleaving enzyme) b antikoerper, furin, paired basic amino acid cleaving enzyme L homeolog antikoerper, furin (paired basic amino acid cleaving enzyme) antikoerper, FURIN antikoerper, furina antikoerper, furinb antikoerper, furin antikoerper, furin.L antikoerper, Furin antikoerper
    Hintergrund
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140 and may play a role in tumor progression. This gene is located in close proximity to family member proprotein convertase subtilisin/kexin type 6 and upstream of the FES oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],FUR, PACE, PCSK3, SPC1,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Notch Signaling Pathway,Signal Transduction,Ubiquitin,FURIN
    Molekulargewicht
    87kDa
    Gen-ID
    5045
    UniProt
    P09958
    Pathways
    Notch Signalweg, Neurotrophin Signalübertragung
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