GSPT1 Antikörper (AA 138-420)

Produktnummer ABIN7267321

Produktdetails anti-GSPT1 Antikörper

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Bindungsspezifität: AA 138-420

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSPT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: GSPT1 Rabbit pAb

Sequenz: SMELSEPIEN GETEMSPEES WEHKEEISEA EPGGGSLGDG RPPEESAHEM MEEEEEIPKP KSVVAPPGAP KKEHVNVVFI GHVDAGKSTI GGQIMYLTGM VDKRTLEKYE REAKEKNRET WYLSWALDTN QEERDKGKTV EVGRAYFETE KKHFTILDAP GHKSFVPNMI GGASQADLAV LVISARKGEF ETGFEKGGQT REHAMLAKTA GVKHLIVLIN KMDDPTVNWS NERYEECKEK LVPFLKKVGF NPKKDIHFMP CSGLTGANLK EQSDFCPWYI GLP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 138-420 of human GSPT1 (NP_001123478.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GSPT1

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Andere Bezeichnung: GSPT1 (GSPT1 Produkte)

Hintergrund: Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity. Stimulates the activity of ETF1 (By similarity. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF of mRNA from viruses and cellular genes.,GSPT1,551G9.2,ETF3A,GST1,eRF3a,Epigenetics & Nuclear Signaling,RNA Binding,GSPT1

Molekulargewicht: 55kDa/68kDa

Gen-ID: 2935

UniProt: P15170