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Glutathione Peroxidase 2 Antikörper (AA 100-180)

GPX2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7267435
  • Target Alle Glutathione Peroxidase 2 (GPX2) Antikörper anzeigen
    Glutathione Peroxidase 2 (GPX2)
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-180
    Reaktivität
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 13
    • 1
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 10
    • 2
    • 1
    • 1
    Dieser Glutathione Peroxidase 2 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    GPX2 Rabbit pAb
    Sequenz
    TLVQKCEVNG QNEHPVFAYL KDKLPYPYDD PFSLMTDPKL IIWSPVRRSD VAWNFEKFLI GPEGEPFRRY SRTFPTINIE P
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 100-180 of human GPX2 (NP_002074.2).
    Isotyp
    IgG
    Top Product
    Discover our top product GPX2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Glutathione Peroxidase 2 (GPX2)
    Andere Bezeichnung
    GPX2 (GPX2 Produkte)
    Synonyme
    ATGPX2 antikoerper, GLUTATHIONE PEROXIDASE antikoerper, T9H9.9 antikoerper, T9H9_9 antikoerper, glutathione peroxidase 2 antikoerper, GI-GPx antikoerper, GPRP antikoerper, GPRP-2 antikoerper, GPx-2 antikoerper, GPx-GI antikoerper, GSHPX-GI antikoerper, GSHPx-2 antikoerper, LOC100136264 antikoerper, GSHPx-GI antikoerper, GPX-GI antikoerper, glutathione peroxidase 2 antikoerper, glutathione peroxidase 1 antikoerper, GPX2 antikoerper, gpx1 antikoerper, Gpx2 antikoerper, LELG_01052 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.,GPX2;GI-GPx;GPRP;GPRP-2;GPx-2;GPx-GI;GSHPX-GI;GSHPx-2,Cell Biology & Developmental Biology,Endocrine & Metabolism,GPX2
    Molekulargewicht
    21kDa
    Gen-ID
    2877
    UniProt
    P18283
    Pathways
    Thyroid Hormone Synthesis
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