GSTA3 Antikörper (AA 1-222)

Produktnummer ABIN7267440

Produktdetails anti-GSTA3 Antikörper

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Bindungsspezifität: AA 1-222

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: GSTA3 Rabbit pAb

Sequenz: MAGKPKLHYF NGRGRMEPIR WLLAAAGVEF EEKFIGSAED LGKLRNDGSL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYTEGMA DLNEMILLLP LCRPEEKDAK IALIKEKTKS RYFPAFEKVL QSHGQDYLVG NKLSRADISL VELLYYVEEL DSSLISNFPL LKALKTRISN LPTVKKFLQP GSPRKPPADA KALEEARKIF RF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA3 (NP_000838.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GSTA3

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Andere Bezeichnung: GSTA3 (GSTA3 Produkte)

Synonyme: GSTA3 antikoerper, GST antikoerper, GSTA1 antikoerper, GSTA3-3 antikoerper, GTA3 antikoerper, GSTA2 antikoerper, Gst2-3 antikoerper, Yc2 antikoerper, glutathione S-transferase alpha 3 antikoerper, glutathione S-transferase A2 antikoerper, glutathione S-transferase antikoerper, glutathione S-transferase, alpha 3 antikoerper, glutathione S-transferase Yc antikoerper, GSTA3 antikoerper, LOC474938 antikoerper, gsta3 antikoerper, Gsta3 antikoerper, LOC100328911 antikoerper

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008],GSTA3,GSTA3-3,GTA3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Drug metabolism,GSTA3

Molekulargewicht: 25kDa

Gen-ID: 2940

UniProt: Q16772