GCH1 Antikörper (AA 1-250)

Produktnummer ABIN7267525

Produktdetails anti-GCH1 Antikörper

Target: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: GCH1 Rabbit pAb

Sequenz: MEKGPVRAPA EKPRGARCSN GFPERDPPRP GPSRPAEKPP RPEAKSAQPA DGWKGERPRS EEDNELNLPN LAAAYSSILS SLGENPQRQG LLKTPWRAAS AMQFFTKGYQ ETISDVLNDA IFDEDHDEMV IVKDIDMFSM CEHHLVPFVG KVHIGYLPNK QVLGLSKLAR IVEIYSRRLQ VQERLTKQIA VAITEALRPA GVGVVVEATH MCMVMRGVQK MNSKTVTSTM LGVFREDPKT REEFLTLIRS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GCH1 (NP_000152.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GCH1

Target: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Andere Bezeichnung: GCH1 (GCH1 Produkte)

Synonyme: DYT14 antikoerper, DYT5 antikoerper, DYT5a antikoerper, GCH antikoerper, GTP-CH-1 antikoerper, GTPCH1 antikoerper, HPABH4B antikoerper, GTP-CH antikoerper, GTPCH antikoerper, Gch antikoerper, MGC89622 antikoerper, gch1a antikoerper, wu:fc16b10 antikoerper, zgc:195269 antikoerper, GTP cyclohydrolase 1 antikoerper, GTP cyclohydrolase 1-like antikoerper, GCH1 antikoerper, Gch1 antikoerper, gch1 antikoerper, Weevi_1190 antikoerper, Halhy_0838 antikoerper, Sinme_1220 antikoerper, Sphch_1077 antikoerper, LOC100136794 antikoerper

Hintergrund: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.,GCH1,DYT14,DYT5,DYT5a,GCH,GTP-CH-1,GTPCH1,HPABH4B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,GCH1

Molekulargewicht: 23kDa/25kDa/27kDa

Gen-ID: 2643

UniProt: P30793