INPP5E Antikörper (AA 510-630)

Produktnummer ABIN7267883

Produktdetails anti-INPP5E Antikörper

Target: INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))

Bindungsspezifität: AA 510-630

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INPP5E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: INPP5E Rabbit pAb

Sequenz: LIREMRKGSI FKGFQEPDIH FLPSYKFDIG KDTYDSTSKQ RTPSYTDRVL YRSRHKGDIC PVSYSSCPGI KTSDHRPVYG LFRVKVRPGR DNIPLAAGKF DRELYLLGIK RRISKEIQRQ Q

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 510-630 of human INPP5E (NP_063945.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu INPP5E

Target: INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))

Andere Bezeichnung: INPP5E (INPP5E Produkte)

Synonyme: 1200002L24Rik antikoerper, 72kDa antikoerper, mKIAA0123 antikoerper, CORS1 antikoerper, CPD4 antikoerper, JBTS1 antikoerper, MORMS antikoerper, PPI5PIV antikoerper, PMPCA antikoerper, inositol polyphosphate-5-phosphatase E antikoerper, Inpp5e antikoerper, INPP5E antikoerper

Hintergrund: The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome, a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],CORS1,CPD4,JBTS1,MORMS,PPI5PIV,pharbin,INPP5E,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,INPP5E

Molekulargewicht: 66kDa/70kDa

Gen-ID: 56623

UniProt: Q9NRR6