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IFITM2 Antikörper (AA 1-100)

IFITM2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7267949
  • Target Alle IFITM2 Antikörper anzeigen
    IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    Human
    Wirt
    • 32
    • 4
    • 1
    Kaninchen
    Klonalität
    • 35
    • 2
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IFITM2 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 23
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    IFITM2 Rabbit pAb
    Sequenz
    MNHIVQTFSP VNSGQPPNYE MLKEEQEVAM LGVPHNPAPP MSTVIHIRSE TSVPDHVVWS LFNTLFMNTC CLGFIAFAYS VKSRDRKMVG DVTGAQAYAS
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFITM2 (NP_006426.2).
    Isotyp
    IgG
    Top Product
    Discover our top product IFITM2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))
    Andere Bezeichnung
    IFITM2 (IFITM2 Produkte)
    Synonyme
    1-8D antikoerper, DSPA2c antikoerper, Ifitm3l antikoerper, fragilis3 antikoerper, mil-3 antikoerper, Ifitml antikoerper, interferon induced transmembrane protein 2 antikoerper, IFITM2 antikoerper, Ifitm2 antikoerper
    Hintergrund
    IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2, Marburg virus (MARV, Ebola virus (EBOV, Dengue virus (DNV, West Nile virus (WNV, human immunodeficiency virus type 1 (HIV-1, hepatitis C virus (HCV and vesicular stomatitis virus (VSV. Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV and SARS-CoV-2 S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. In hepatocytes, IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation. IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome.,IFITM2,1-8D,DSPA2c,Cancer,Tumor immunology,Tumor-associated antigens,Immunology & Inflammation,Cytokines,Interferons,Cell Intrinsic Innate Immunity Signaling Pathway,IFITM2
    Molekulargewicht
    14kDa
    Gen-ID
    10581
    UniProt
    Q01629
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