IQSEC1 Antikörper (AA 180-380)

Produktnummer ABIN7268018

Produktdetails anti-IQSEC1 Antikörper

Target: IQSEC1 (IQ Motif and Sec7 Domain 1 (IQSEC1))

Bindungsspezifität: AA 180-380

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQSEC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: IQSEC1 Rabbit pAb

Sequenz: SFEGPEKVHS SYFEGKQVSV TNDGSQLGAL VSPECGDLSE PTTLKSPAPS SDFADAITEL EDAFSRQVKS LAESIDDALN CRSLHTEEAP ALDAARARDT EPQTALHGMD HRKLDEMTAS YSDVTLYIDE EELSPPLPLS QAGDRPSSTE SDLRLRAGGA APDYWALAHK EDKADTDTSC RSTPSLERQE QRLRVEHLPL L

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human IQSEC1 (NP_055684.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IQSEC1

Target: IQSEC1 (IQ Motif and Sec7 Domain 1 (IQSEC1))

Andere Bezeichnung: IQSEC1 (IQSEC1 Produkte)

Synonyme: ARF-GEP100 antikoerper, ARFGEP100 antikoerper, BRAG2 antikoerper, GEP100 antikoerper, AW561907 antikoerper, BC026481 antikoerper, D6Ertd349e antikoerper, cI-43 antikoerper, mKIAA0763 antikoerper, IQ motif and Sec7 domain 1 antikoerper, IQSEC1 antikoerper, Iqsec1 antikoerper

Hintergrund: Guanine nucleotide exchange factor for ARF1 and ARF6. Guanine nucleotide exchange factor activity is enhanced by lipid binding. Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalization of beta-1 integrin. Involved in neuronal development (Probable. In neurons, plays a role in the control of vesicle formation by endocytoc cargo. Upon long term depression, interacts with GRIA2 and mediates the activation of ARF6 to internalize synaptic AMPAR receptors (By similarity.,IQSEC1,ARF-GEP100,ARFGEP100,BRAG2,GEP100,Cancer,Signal Transduction,G protein signaling,Signal Transduction,ErbB-HER Signaling Pathway,IQSEC1

Molekulargewicht: 108kDa

Gen-ID: 9922

UniProt: Q6DN90