JARID2 Antikörper

Produktnummer ABIN7268047

Produktdetails anti-JARID2 Antikörper

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser JARID2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: JARID2 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human JARID2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu JARID2

Target: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Andere Bezeichnung: JARID2 (JARID2 Produkte)

Synonyme: JMJ antikoerper, Jmj antikoerper, jumonji antikoerper, JARID2 antikoerper, jarid2 antikoerper, jmj antikoerper, si:dkey-211c3.1 antikoerper, Jumonji antikoerper, jarid2-a antikoerper, jarid2-b antikoerper, jarid2.S antikoerper, jarid2b antikoerper, jumonji and AT-rich interaction domain containing 2 antikoerper, jumonji, AT rich interactive domain 2 antikoerper, jumonji, AT rich interactive domain 2a antikoerper, jumonji, AT rich interactive domain 2b antikoerper, jumonji and AT-rich interaction domain containing 2 L homeolog antikoerper, JARID2 antikoerper, Jarid2 antikoerper, jarid2a antikoerper, jarid2 antikoerper, jarid2b antikoerper, jarid2.L antikoerper

Hintergrund: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012],JMJ,Epigenetics & Nuclear Signaling,Neuroscience,JARID2

Molekulargewicht: 139kDa

Gen-ID: 3720

UniProt: Q92833

Pathways: Chromatin Binding