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LDLR Antikörper (C-Term)

KO Validated LDLR Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7268296
  • Target Alle LDLR Antikörper anzeigen
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    Bindungsspezifität
    • 16
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 80
    • 45
    • 32
    • 17
    • 16
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 68
    • 13
    • 5
    Kaninchen
    Klonalität
    • 67
    • 19
    Polyklonal
    Konjugat
    • 44
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LDLR Antikörper ist unkonjugiert
    Applikation
    • 58
    • 35
    • 26
    • 18
    • 13
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Verwendungszweck
    [KO Validated] LDL Receptor (LDLR) Rabbit pAb
    Sequenz
    VFLCLGVFLL WKNWRLKNIN SINFDNPVYQ KTTEDEVHIC HNQDGYSYPS RQMVSLEDDV A
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Güteklasse
    KO Validated
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 800 to the C-terminus of human LDL Receptor (LDLR) (NP_000518.1).
    Isotyp
    IgG
    Top Product
    Discover our top product LDLR Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    Andere Bezeichnung
    LDLR (LDLR Produkte)
    Synonyme
    FH antikoerper, FHC antikoerper, LDLCQ2 antikoerper, Hlb301 antikoerper, LDLRA antikoerper, LDLA antikoerper, LDL receptor-2 antikoerper, fhc antikoerper, ldlcq2 antikoerper, ldlr antikoerper, ldlr2-a antikoerper, LDL receptor 1 antikoerper, ldlr-a antikoerper, ldlr-b antikoerper, low density lipoprotein receptor antikoerper, low density lipoprotein receptor a antikoerper, low density lipoprotein receptor S homeolog antikoerper, low density lipoprotein receptor L homeolog antikoerper, LDLR antikoerper, Ldlr antikoerper, ldlra antikoerper, ldlr.S antikoerper, ldlr.L antikoerper
    Hintergrund
    The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.,LDLR,FH,FHC,LDLCQ2,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,LDLR
    Molekulargewicht
    75kDa/76kDa/82kDa/90kDa/95kDa
    Gen-ID
    3949
    UniProt
    P01130
    Pathways
    Hepatitis C, Lipid Metabolism
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