MBTPS1 Antikörper (AA 803-1052)

Produktnummer ABIN7268470

Produktdetails anti-MBTPS1 Antikörper

Target: MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))

Bindungsspezifität: AA 803-1052

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBTPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: MBTPS1 Rabbit pAb

Sequenz: ITQTFKDQGL EVLKQETAVV ENVPILGLYQ IPAEGGGRIV LYGDSNCLDD SHRQKDCFWL LDALLQYTSY GVTPPSLSHS GNRQRPPSGA GSVTPERMEG NHLHRYSKVL EAHLGDPKPR PLPACPRLSW AKPQPLNETA PSNLWKHQKL LSIDLDKVVL PNFRSNRPQV RPLSPGESGA WDIPGGIMPG RYNQEVGQTI PVFAFLGAMV VLAFFVVQIN KAKSRPKRRK PRVKRPQLMQ QVHPPKTPSV

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MBTPS1

Target: MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))

Andere Bezeichnung: MBTPS1 (MBTPS1 Produkte)

Synonyme: PCSK8 antikoerper, S1P antikoerper, SKI-1 antikoerper, 0610038M03Rik antikoerper, AV003995 antikoerper, Ski1 antikoerper, mKIAA0091 antikoerper, S1p antikoerper, Ski-1 antikoerper, membrane bound transcription factor peptidase, site 1 antikoerper, membrane-bound transcription factor peptidase, site 1 antikoerper, MBTPS1 antikoerper, Mbtps1 antikoerper

Hintergrund: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.,MBTPS1,PCSK8,S1P,SKI-1,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Lipid Metabolism,MBTPS1

Molekulargewicht: 117kDa

Gen-ID: 8720

UniProt: Q14703

Pathways: ER-Nucleus Signaling