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GNPTAB Antikörper (AA 42-350)

GNPTAB Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7268770
  • Target Alle GNPTAB Antikörper anzeigen
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    Bindungsspezifität
    • 15
    • 15
    • 2
    • 1
    AA 42-350
    Reaktivität
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser GNPTAB Antikörper ist unkonjugiert
    Applikation
    • 26
    • 26
    • 18
    • 6
    • 6
    • 6
    • 2
    Western Blotting (WB)
    Verwendungszweck
    GNPTAB Rabbit pAb
    Sequenz
    LEWSRDQYHV LFDSYRDNIA GKSFQNRLCL PMPIDVVYTW VNGTDLELLK ELQQVREQME EEQKAMREIL GKNTTEPTKK SEKQLECLLT HCIKVPMLVL DPALPANITL KDLPSLYPSF HSASDIFNVA KPKNPSTNVS VVVFDSTKDV EDAHSGLLKG NSRQTVWRGY LTTDKEVPGL VLMQDLAFLS GFPPTFKETN QLKTKLPENL SSKVKLLQLY SEASVALLKL NNPKDFQELN KQTKKNMTID GKELTISPAY LLWDLSAISQ SKQDEDISAS RFEDNEELRY SLRSIERHAP WVRNIFIVT
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 42-350 of human GNPTAB (NP_077288.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    Andere Bezeichnung
    GNPTAB (GNPTAB Produkte)
    Synonyme
    si:ch211-234f20.3 antikoerper, wu:fd55d09 antikoerper, zgc:122985 antikoerper, zgc:158502 antikoerper, GNPTA antikoerper, ICD antikoerper, EG432486 antikoerper, mKIAA1208 antikoerper, RGD1564821 antikoerper, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits antikoerper, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antikoerper, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta antikoerper, GNPTAB antikoerper, gnptab antikoerper, LOC100175423 antikoerper, Gnptab antikoerper
    Hintergrund
    This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.,GNPTAB,GNPTA,ICD,Cancer,Signal Transduction,Endocrine & Metabolism,GNPTAB
    Molekulargewicht
    55kDa/143kDa
    Gen-ID
    79158
    UniProt
    Q3T906
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