GNPTAB Antikörper (AA 42-350)

Produktnummer ABIN7268770

Produktdetails anti-GNPTAB Antikörper

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Bindungsspezifität: AA 42-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNPTAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: GNPTAB Rabbit pAb

Sequenz: LEWSRDQYHV LFDSYRDNIA GKSFQNRLCL PMPIDVVYTW VNGTDLELLK ELQQVREQME EEQKAMREIL GKNTTEPTKK SEKQLECLLT HCIKVPMLVL DPALPANITL KDLPSLYPSF HSASDIFNVA KPKNPSTNVS VVVFDSTKDV EDAHSGLLKG NSRQTVWRGY LTTDKEVPGL VLMQDLAFLS GFPPTFKETN QLKTKLPENL SSKVKLLQLY SEASVALLKL NNPKDFQELN KQTKKNMTID GKELTISPAY LLWDLSAISQ SKQDEDISAS RFEDNEELRY SLRSIERHAP WVRNIFIVT

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-350 of human GNPTAB (NP_077288.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GNPTAB

Target: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Andere Bezeichnung: GNPTAB (GNPTAB Produkte)

Hintergrund: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.,GNPTAB,GNPTA,ICD,Cancer,Signal Transduction,Endocrine & Metabolism,GNPTAB

Molekulargewicht: 55kDa/143kDa

Gen-ID: 79158

UniProt: Q3T906