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NLRP10 Antikörper (AA 1-300)

NLRP10 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7268936
  • Target Alle NLRP10 Antikörper anzeigen
    NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    AA 1-300
    Reaktivität
    • 47
    • 9
    • 1
    Human
    Wirt
    • 46
    • 1
    • 1
    Kaninchen
    Klonalität
    • 47
    • 1
    Polyklonal
    Konjugat
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NLRP10 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 22
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    NLRP10 Rabbit pAb
    Sequenz
    MAMAKARKPR EALLWALSDL EENDFKKLKF YLRDMTLSEG QPPLARGELE GLIPVDLAEL LISKYGEKEA VKVVLKGLKV MNLLELVDQL SHICLHDYRE VYREHVRCLE EWQEAGVNGR YNQVLLVAKP SSESPESLAC PFPEQELESV TVEALFDSGE KPSLAPSLVV LQGSAGTGKT TLARKMVLDW ATGTLYPGRF DYVFYVSCKE VVLLLESKLE QLLFWCCGDN QAPVTEILRQ PERLLFILDG FDELQRPFEE KLKKRGLSPK ESLLHLLIRR HTLPTCSLLI TTRPLALRNL
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NLRP10 (NP_789791.1).
    Isotyp
    IgG
    Top Product
    Discover our top product NLRP10 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
    Andere Bezeichnung
    NLRP10 (NLRP10 Produkte)
    Synonyme
    CLR11.1 antikoerper, NALP10 antikoerper, NOD8 antikoerper, PAN5 antikoerper, PYNOD antikoerper, 6430548I20Rik antikoerper, Nalp10 antikoerper, Napl10 antikoerper, Pynod antikoerper, NLR family pyrin domain containing 10 antikoerper, NLR family, pyrin domain containing 10 antikoerper, NLRP10 antikoerper, Nlrp10 antikoerper
    Hintergrund
    Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.,NLRP10,CLR11.1,NALP10,NOD8,PAN5,PYNOD,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP10
    Molekulargewicht
    75kDa
    Gen-ID
    338322
    UniProt
    Q86W26
    Pathways
    Inflammasome
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