NLRP6 Antikörper (AA 100-200)

Produktnummer ABIN7268941

Produktdetails anti-NLRP6 Antikörper

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Bindungsspezifität: AA 100-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: NLRP6 Rabbit pAb

Sequenz: RRLQRLGLGS GTLLSVSEYK KKYREHVLQL HARVKERNAR SVKITKRFTK LLIAPESAAP EEAMGPAEEP EPGRARRSDT HTFNRLFRRD EEGRRPLTVV L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NLRP6 (NP_001263629.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Andere Bezeichnung: NLRP6 (NLRP6 Produkte)

Synonyme: NLRP6 antikoerper, NALP6 antikoerper, AVR antikoerper, CLR11.4 antikoerper, NAVR antikoerper, NAVR/AVR antikoerper, PAN3 antikoerper, PYPAF5 antikoerper, AI504961 antikoerper, Avr antikoerper, Nalp6 antikoerper, Navr antikoerper, Navr/Avr antikoerper, Pypaf5 antikoerper, NLR family pyrin domain containing 6 antikoerper, NLR family, pyrin domain containing 6 antikoerper, NLRP6 antikoerper, Nlrp6 antikoerper

Hintergrund: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.,NLRP6,AVR,CLR11.4,NALP6,NAVR,NAVR/AVR,PAN3,PYPAF5,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP6

Molekulargewicht: 99kDa

Gen-ID: 171389

UniProt: P59044

Pathways: Inflammasome