NR1H2 Antikörper (AA 150-250)

Produktnummer ABIN7269011

Produktdetails anti-NR1H2 Antikörper

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Bindungsspezifität: AA 150-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1H2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: NR1H2 Rabbit pAb

Sequenz: KEAGMREQCV LSEEQIRKKK IRKQQQQESQ SQSQSPVGPQ GSSSSASGPG ASPGGSEAGS QGSGEGEGVQ LTAAQELMIQ QLVAAQLQCN KRSFSDQPKV T

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human NR1H2 (NP_009052.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NR1H2

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Andere Bezeichnung: NR1H2 (NR1H2 Produkte)

Synonyme: NR1H2 antikoerper, lxr-b antikoerper, lxrb antikoerper, ner antikoerper, ner-i antikoerper, rip15 antikoerper, unr antikoerper, DKFZp468A0622 antikoerper, AI194859 antikoerper, LXR antikoerper, LXRB antikoerper, LXRbeta antikoerper, NER1 antikoerper, OR-1 antikoerper, RIP15 antikoerper, UR antikoerper, Unr antikoerper, Unr2 antikoerper, LXR-b antikoerper, NER antikoerper, NER-I antikoerper, UNR antikoerper, nuclear receptor subfamily 1 group H member 2 antikoerper, nuclear receptor subfamily 1, group H, member 2 antikoerper, nuclear receptor subfamily 1 group H member 2 L homeolog antikoerper, NR1H2 antikoerper, nr1h2 antikoerper, Nr1h2 antikoerper, nr1h2.L antikoerper

Hintergrund: The liver X receptors, LXRA (NR1H3, MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs, see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010],NR1H2,LXR-b,LXRB,NER,NER-I,RIP15,UNR,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,NR1H2

Molekulargewicht: 39kDa/50kDa

Gen-ID: 7376

UniProt: P55055

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding